Health Supplements: An analysis

Health Supplements: An analysis CHAPTER 1 The prevalence used of health supplements especially multivitamins and minerals in many developed counteries are widened eventhough their effectiveness is unclearly determined (Rock , 2007). Based on the data collected by National Health and Nutrition Examination Survey (NHANES) 1999-2000, 52 percent of US adults reported taking a dietary supplement in the past month and 35 percent is reported on regular use of a multivitamin-multimineral product. Marketing data from Nutrition Business Journal of year 1997 till 2001 show a dramatic increase in supplement sales and estimated total approximately $ 18.8 billion in 2003. In Malaysia, according to the data published by Icon Health Publication from R D Committee at INSTEAD, the latent demand for vitamin and dietary supplement has growing increasing from year to year. Since the use of health supplements continues to expand in future, thus investigating of preliminary reason behind this trend is important. Supplement consumption usually occurs in the context of achieving or maintaining a healthy lifestyle. Several studies have been suggested that individuals might tend to use health supplements in order to compensate for unhealthy behaviours (Hilliam, 1996; Kirk et al., 1999; Radimer et al., 2000). One of the important reason that contribute to the increased use of health supplement is widely availability of these agents, in part because of the minimal regulatory requirements for safety and efficacy compared with regulatory requirements for drugs. Despite the fact that health supplements are not classified as drugs by the US Food and Drug Administration (FDA), the 1994 Dietary Supplement Health and Education Act allows manufacturers to make claims intended to attract public opinion regarding the benefits on the use of these supplement products. Under DSHEA, product labels cannot claim to diagnose, treat, cure or prevent any disease but it only claims to support the structure and function of the body.  [1]  Basically, consumption of health supplements can also be categorized as one of the type of c omplementary or alternative medicine (CAM). 1.2 Significance of the study Anecdotally, there is an increasing use of health supplements among Malaysian. However, relatively little is known about the patterns of use of health supplements among them. Therefore, there is a need for continued research in order to provide more knowledge related to the benefit of supplement use. To our knowledge, only one study conducted by International Medical University, has focused specifically on the usage and opinion among health sciences students on the dietary supplements. Eventhough usage of health supplement is prevalent but there are only a few published reports (Mazlan, 1990; Safiah, 2002). In parallel with the implementation of National Plan of Action for Nutrition II of Malaysia (NPANM), there is a need for continued research in order to investigate the use, attitudes and knowledge of health supplements among urban adults in Klang Valley which still represents the area with the highest prevalence of health supplements user in Malaysia. 1.3 Objectives The purpose of this study was to assess the use of health supplements among Malaysians urban adults . This study not only focused on herbal supplements but it also include functional foods, nutrient and botanical products available in the market. Besides, we like to determine whether attitudes are better predictor of adults intentions to use health supplements than are subjective norms. Last but not least is to assess knowledge concerning the safety of health supplements among urban adults. CHAPTER 2 LITERATURE REVIEW 2.1 Health supplement 2.1.1 Definition of health supplement Health supplement is a term that also commonly known as dietary supplement, nutraceutical supplement or nutritional supplement. Eventhough this term has been used interchangeably, but the meaning of them is still same. In early 1990s, a nutraceutical term was coined by Dr. Stephen DeFelice and it was defined concisely as any substance either food or a part of food. It has a wider range from specific diet, isolated nutrients, processed foods, dietary supplements to genetically modified foods and also include herbal products. It was intended to be use to provides health benefits to the end user (Barnett et al., 1996). Before year 1994, the health supplement was subjected to the same regulatory requirement as other food. However, in October 1994, the President Clinton was assigned a new act under FDA regulations that known as Dietary Supplement Health and Education Act. According to the DSHEA, dietary supplement is defined as a product that intended to be taken orally in order to supple ment the diet in which it contains a dietary ingredient. The dietary ingredients in these products may include vitamins, minerals, herbs or other botanicals, amino acids, and substances such as enzymes, organ tissues, glandulars and metabolites. It can also be extracts or concentrates, and may be found in many forms such as tablets, capsules, softgels, gelcaps, liquids or powders (U.S Food and Drug Administration, 1995). Whatever dosage form it is, this dietary ingredient is not considered as a drug. In case of a drug, it was subjected to undergo some procedures in order to be clinically proven safe to be used. However, dietary supplement was treated reverse to this way since that it was considered safe until proven unsafe. In addition, dietary ingredient could be used in dietary supplement without a need to get approval from FDA as food additive and generally recognised as safe (GRAS) ingredients (Susan Onel, 2005). Due to the minimal regulatory requirements of safety and its efficacy, therefore the health supplement become more widely available and this contributed to increase of its used (Bardia et al., 2007). However, in case of a new dietary ingredient present in the product then the manufacturers of dietary supplement must have to provide FDA with evidence by submission of the products safety data of at least 75 days prior to its release to the public. This dietary ingredient was considered as a new ones if it was not marketed in U.S before October 15, 1994 (Cohen, 2000). 2.1.2 Definition of health supplement user Generally, health supplement users are those healthy people who are seeking for supplements as a one of several alternatives for improving health (Sheldon Pelletier, 2003). In U.S, it has been estimated that approximately half of their adult population considered as users of health supplements (Robson et al., 2008 ; Radimer et al., 2004). A study done by Knudsen et al. in year 1997 to 1998 at two Danish cities was defined a health supplement user as a person who consumed at least one type of supplements within a period of time of the survey. Basically, Knudsen and his colleagues determined those supplement users based on their frequency intake. Result indicated that from 2758 of supplement users about 27 percent of them took more than one health supplement per day and twelve percent took three or more per day (Knudsen et al., 2002). In the present study persons who consumed any health supplement at least once in a year has been considered as dietary or health supplement users. In this study, they defined health supplement users into three groups which are daily user, weekly user and seldom user. The daily users are those who reported use of any health supplement once a day or more for the past 12 months whereas weekly users are those who reported use once a week or more but must be less than once a day for the past 12 months and seldom users are those people who reported use once a year or more but less than once a week for the past 12 months (Imai et al., 2006). 2.1.3 Types of health supplements With the increased in health awareness regarding the use of health supplements, the public is flooded by numerous health supplement products which are frequently advertised through the various media. Thus, there are many types of health supplements that have been practically used by the supplement user. 2.1.3.1 Vitamin Vitamin is a group of complex organic compounds that present in small amounts in natural foodstuffs which are play an essential role for the body to regulate normal metabolism and lack of which in the diet causes deficiency diseases (McDowell, 2000). Since vitamin can be found in daily food consumption thus for a normal healthy people intake of vitamin supplement is unnecessary. This is because overconsumption of certain vitamin such as vitamin A may lead to reversible Acute hypervitaminosis that occur after ingestion of more than or equal to 500,000 IU (over 100 times the RDA) by adults (Bendich Langseth, 1989). According to the survey done among 129 doctors working at hospitals in Kota Bharu, the results showed that the health supplements commonly used were multivitamins and minerals (92.3 percent) whereas prevalence used of vitamin C is 26.9 percent (Rohana Zulkifli, 2007). The types and usage patterns of health supplements used as shown in Table 2.1 Table 2.1 : Types and used patterns of health supplements among doctors Rank Supplement/s Regular users Sporadic users Total (%) 1 MVT plus minerals 14 1 15 (17.9) 2 Vitamin Bco 12 3 15 (17.9) 3 Vitamin C 10 1 11 (13.1) 4 Garlic 7 0 7 (8.3) 5 MVT only 5 1 6 (7.1) 6 Traditional 4 1 5 (6.0) 7 Lecithin 4 0 4 (4.8) 8 Prenatal vitamins 3 0 3 (3.6) 9 Vitamin E 3 0 3 (3.6) 10 Fish oil 2 1 3 (3.6) 11 Ginseng 2 1 3 (3.6) 12 Iron/Folic acid 2 0 2 (2.4) 13 Bee Pollen 1 1 2 (2.4) 14 Others 5 0 5 (6.0) TOTAL 74 10 84 (100.0) Source : Malaysian Journal of Public Health Medicine 2007, Vol. 7(1):60-63 2.1.3.2 Mineral Minerals are nonorganic substances found in all body tissues and fluids such as bones, teeth, brain, liver, muscle, blood and nerve cells. They are required in modest amounts for the maintenance of structural integrity of essential molecules and development of optimal physiological function (Lukaski, 1995). Since minerals cannot be synthesized by the body therefore they must be consumed through a healthy diet. Based on the data from the NILS-LSA done in Japan, about 55 percent of males and 61 percent of females were consumed some type of health supplements and revealed that calcium was the most popular mineral consumed by both sexes ( Imai et al., 2006). In addition the study done by Chandra and his colleagues were investigated the respondents regarding to their reasons for consuming mineral supplements and their knowledge on mineral supplements. Thus, the finding of this study revealed that the most prevelent reason for consuming mineral supplements is to feel better and their lev el of knowledge on types and benefits of mineral supplements is moderate (Chandra, Miller and Willis, 2005). 2.1.3.4 Herb and other botanicals There are many different herbal and botanical supplements available on the market. Thus, approximately one third of U.S adults reported using botanical supplements (Harris Polls, 1998). In addition, in year 1999 the Chemical Market Reporter revealed that the botanical and herbal market generated approximately $3.9 billion in sales (Anonymous, 1999). A survey shown that about 57.3 percent of adults favourably used herbs in order to treat a specific illnesses (Bardia et al., 2007). According to the survey done by Newberry et al. in 2001 found that 71 of 132 respondents reported they took NVNM health supplements in order to promote good health, prevent disease and to enhance immune system. Most commonly reported used of these NVNM are includes Echinacea, ginseng, St Johns Wort, gingko biloba, ephedra, saw palmetto, chamomile and garlic. From 71 respondents who reported taken NVNM to promote good health about 77.5 percent claimed them to be effective. In addition, 50 respondents reported taken NVNM such as chamomile, gingko biloba, kava kava and St Johns wort in order to relieve depression and anxiety. Fortunately, survey indicated that 43 of 50 respondents perceived them to be effective (Newberry et al., 2001). 2.1.3.5 Amino acid Our cell is made up from different kind of the building blocks of proteins. This body protein that is called amino acid. Some of the amino acid is been synthesized within the body is called an non-essential amino acid whereas other half cannot be synthesized and must be absorbed and preformed from the gastro-intestinal tracts. This is called essential amino acid which is can be obtained from the food and amino acid supplements. A survey done among college student revealed that 17 out of 272 college students took the putative ergogenic which is commonly considered as amino acid sub-category. The prevalent reason claimed by college students regarding the used of these supplements is to enhance their athletic performance (Newberry et al., 2001). 2.3 Pattern of health supplements used From NHANES surveys discovered that the most common pattern of supplement use among US population appeared to be the use of single product which is 55 percent. Whereas 66 percent of supplement users took more than one product and only 13 percent took five or more (Sandler et al., 2001). A survey of 21 923 adults residing in the metropolitan boroughs of Bolton and Wigan, UK revealed 35.4 percent took at least one dietary supplement, 72.2 percent were taking one product whereas 27.8 percent taking two or more products. About 12.6 percent reported eating at least five portions of fruits and vegetables per day and 43.5 percent eating at least one portion of oil-rich fish per week. The use of health supplements was positively correlated with the pattern of eating at least five portions of fruits and vegetables per day (adjusted OR 1.41). Correspondingly, consumption of fish-oil supplements was higher among those eating one portion or more of oil-rich fish per week (adjusted OR 1.50) (Harr ison et al., 2004). Besides, a result of the survey also indicated that among women who were reported as regular supplement user, the most usually reported health supplements used were calcium with 60.3 percent user and 20.3 percent for glucosamine. In contrast, most commonly reported health supplements used by men were vitamin C (37.4 percent) and garlic (18.9 percent) (Robson et al., 2008). 2.4 Prevalence use of health supplements Comparison studies between NHANES 1999-2000 and previous NHANES survey which used same methodology suggested that supplement use has increased (Radimer et al., 2004). A previous study has indicated that most of the supplements have been used in order to promote general health, treat or prevent symptomatic conditions and chronic ailments (Bardia et al., 2007). In 2003 Satia-Abouta et al. study had found that supplements tend to be taken by the people that have been diagnosed with certain medical conditions than others and commented that, although some people take supplements based on efficacy but many do not. A survey result was indicated that supplement use was common among Whites, women, persons with age of 50 years and older and college educated with degree or more (Sheldon Pelletier, 2003 ; Shi et al., 2005). 2.4.1 Sociodemographic In research article by Block and Subar (1990) based on 1987 National Health Interview Survey, they investigate about the used of vitamin and mineral supplements in relation to demographics and amounts of nutrients consumed. This NHIS is a national probability survey among US population. It is the first national studies to address specifically supplement use among Hispanic population. The sample consisted of 22,080 adults of all races aged 18-99 years. A result of the survey revealed that user of vitamin and mineral supplements were slightly more women than were men of the same age and race. Survey shows that among white women within the age ranges 55-64 years, their daily usage are 39.9 percent and 38.4 percent among age ranges 65-74 years. However, among age 75 years and more it is slightly declined (34.9 percent). This indicated that usage pattern tended to increase with age which happened similarly within other sex-age categories. Based on sex-race categories, non-Hispanic whites women show the highest rates of use compared with all other races and Hispanic women show rate intermediate between those of whites and blacks (Blocks Subar, 1990 ; Jasti, Siega-Riz Bentley, 2003). Demographic data regarding income, education, and occupation show that strong socioeconomic influences upon whether individuals take supplements. From the study done by Jong et.al in 2002 revealed that the consumption behaviour towards variety of foods and supplements were associated with demographic and lifestyle characteristics. Result showed that participants in the middle and high education groups were more likely to use supplements containing Echinacea or multivitamin and minerals than individuals with lower education groups. Shi et.al in year 2005 also indicated that the intake of vitamin either in the form of tablets or capsules was significantly common among women and highly educated subjects. 2.4.4 Cultural Factors A study done by Williams et al. in 1996 indicated that cultural factor also influence in supplement use behavior. Based on ethnographic study of iron and folic acid supplementation among women of reproductive age in developing counteries, they found that cultural factors is plays role in supplement use behaviors (Williams et al., 1996). In addition to demographic determinants of supplement use, understanding of cultural factors also considered as crucial for the success of efforts to encourage supplement use in vulnerable population groups (Jasti, Siega-Riz Bentley, 2003). 2.5 Attitude and Behaviour Toward Supplementation Supplement users have been characterized as tend to be healthy people by having a positive attitude towards their health (Dickinson, 2002). In a study done on two-group design of 113 adults in the U.S, the researchers found that participants who have been diagnosed with health problems and experienced on negative effects of their illness showed likeliness to change their attitude towards supplements (McDonald Nicholson, 2006). However, in a study done by Junko Ishihara and his colleagues revealed something interesting about users attitude toward supplementation. Female supplement users who have been influenced by urban lifestyle showed negative lifestyle factors such as frequent eating out and stressful life which later contributed to moderate drinking among them. Those users might be aware of their unhealthy behaviour, hence they intentionally seek to compensate for it with health supplements (Ishihara et al., 2003). Generally, consumers considered health supplements as a safe product to be taken. However, they might not be aware about a few adverse event that have been reported regarding the unsafe use of these natural products (Ashar Rowland-Seymour, 2008 ; Palmer et al., 2003). Researchers have indicated that overdoses of Vitamin E consumption may result a prolonged bleeding time due to its effect on intrinsic coagulation pathway (McDonald Nicholson, 2006 ; Marsh Coombes, 2006). 2.5.1 Consumer dietary knowledge Knowledge regarding health supplements also influence the usage of supplements among the consumer. Based on health care professional surveyed revealed that supplement use are varied by profession with the highest frequency among nurses (88 percent), physician assistants and nurse practitioners (84 percent) and lowest among trainees (72 percent) and pharmacists (66 percent) (Jasti et al., 2003). This result indicated that health care professionals personal habit may affected whether they will recommend a use of health supplement or not (Frank et al., 2000). Futher indication of the supplement use is strongly associated with increased knowledge about nutrition and health (Dickinson, 2002). From the survey done on 4501 female physicians who participating in the Women Physicians Health Study revealed that half of them took a multivitamin-mineral supplement and most of them are those at high risk of getting disease. For example, those who susceptible in getting heart disease tend to consume antioxidant and those with a history of osteoporosis were nearly three times more likely to consume calcium supplement then those with no history of osteoporosis (Dickinson, 2002 ; Frank, Bendich Denniston, 2000). A study done by Gardiner and her colleagues between September, 2004 and May, 2005 found that nurses were more preferably to use a multivitamin than other professionals whereas students were more likely to use calcium (Gardiner et al., 2006). Basically, the types of health supplements used by HCP in such no differences compare to those used by the general public (Millen et al., 1987 ; Patterson et al., 1999).This result is consistent with previous surveys of HCPs which indicate a positive correlation between higher use, greater knowledge and increased communications with patients about benefit regarding the use of health supplement (Corbin Shapiro, 2002 ; Lindquist, Tracy Savik, 2003 ; Tracy et al., 2005). In case of ordinary users, their knowledge about health supplement also influence the usage of the product. A study done by Peters and his colleagues found that supplements user are those people who seek for self-educated approach by consulting a medical doctor and gathering infor mation from credible media sources such as the Internet (Peters et al., 2003). 2.5.2 Lifestyle As one of the developed countries, Malaysians were experienced a nutritional and lifestyle transition due to urbanization, industrialization and globalization. Thus, these rapid alarming trends have lead to the prevalence case of obesity among Malaysians. A study done by National Health and Morbidity Survey (NHMS III) in 2006 was revealed that 14 percents of the adults were obese with the BMI is more than 30 kg/m2. Therefore, this will increased the consumption intake of certain health supplement product that common use in weight loss management program such as Bitter orange (Ashar Rowland-Seymour, 2008). In the NHANES 1999-2000, data indicated that those with higher body mass index and current smokers shown as a less likelihood of reporting use of health supplements (Dwyer, Garceau Evans, 2001 ; Rock et al., 1997). Nonsmokers were more likely to take supplements than were current smokers (Lyle et al., 1998 ; Patterson et al., 1998 ; Subar Block, 1990). Supplement use also associated with healthy lifestyle, which was similar to the earlier-reported tendency for smoking. For BMI, there was a significant linear decrease of dietary supplement users for higher BMI groups in both sexes (Lyle et al., 1998 ; Newman et al., 1998 ; Subar Block, 1990). Regarding exercise, there was a significant linear increase in those groups who exercise more frequently. Prior studies had reported alcohol consumption in health supplement users as either having no association or as showing more users among moderate drinkers. Women who drank moderately (once a month to 6 times a week) were most likely to be users (Ishihara et al., 2003). Study done on a population-based sample of urban Japanese revealed that subjects who experienced more daily stressors (95% CI) are at more higher level of the consumption of vitamin supplements and vitamin enriched drinks compare to those with fewer daily stressors. OR from this study indicated that intake of vitamin supplements by healthy lifestyles subjects was related with acts to solve problems whereas in subjects with unhealthy lifestyle, reason of intake was associated with daily stressors (Shi et al., 2005). CHAPTER 3 METHODOLOGY 3.1 Study design This was a descriptive and cross sectional study Sample size was determined by using a statistical method 3.2 Participants By using a multistage random strategy,400 subjects aged between 20 to 69 years were selected from large population of adults in Klang Valley. Klang Valley is urban areas that consists of Gombak, Setapak, Kuala Lumpur, Petaling Jaya, Shah Alam and Klang areas. The ethnicity of the participants were unlimited to specific ethnic group only. Participants were identified at area clinics, shopping complex and park. 3.3 Questionnaires A questionnaires was designed to collect information among urban adults regarding their use of health supplements and their attitudes and knowledge toward supplementation of these popular substances. This validated questionnaire was developed from other previous survey and some based on literature review, but we take into account health supplements commonly used in the local setting. This survey questions consisted of four sections. The first section consisted of general demographics information such as gender, race and education. In addition, the participants also will be assessed on their current health status. The second section assessed on the usage of health supplement among those subjects. This part going to find out who took supplements and which ones they took, thus participants will be asked Do you usually take any of these supplements? then subsequent to previous question can be asked. Some products were listed in the questionnaire were the most popular health supplement p roducts in the Malaysia. For completeness, they could add any other health supplement to the list. In the analysis, health supplements were classified into few separate categories such as vitamins, minerals, herbal and other supplements. Question on how they find out about their supplement and how much their are taking each day also possible to be asked. The third session focused on attitudes of participants toward health supplements and the fourth section examined their perception of knowledge concerning the safety of these products. In this questionnaire, the participants will read the questions and statements that have been asked, most of which provided with a true/ false/ dont know or yes/ no/ dont know answer. This questionnaire are provided in the Appendix. 3.4 Statistical Analysis All statistical analyses were conducted by using SPSS version 17 for Window XP. Descriptive statistics such as frequencies, means, standard deviations (SD), percentage were used to describe all the variables. One-way ANOVA was used to determine differences in continuous variables such as gender, age, education and income. Adjusted odd ratios (OR) of each preditors were calculated using multiple logistic regression in order to examine the effects of demographic and lifestyle on use or non-use of health supplements. Multiple logistic regression analysis also been used to identify the independent contribution of attitudes and knowledge toward the probability of use of health supplements. Futhermore, chi-square test also was used in order to find the correlation between qualitative variables at the 5% significance level. A p-value which less than 0.05 represents a significant difference. 3.5 Ethical approval Ethical approval for this survey was obtained from the Research Ethics Committee of Research Management Institute, Universiti Teknologi MARA.

Autism Spectrum Disorder (ASD)

Autism Spectrum Disorder – Causes, Reasons and TreatmentAutism Spectrum Disorder (ASD) is defined as a developmental disability that affects people’s personalities based on how they interact with the world (Magalhaes and Almeida, 2010). However, Sparks and Dager (2012, p. 187) defines ASD as â€Å"a serious neurodevelopmental disorder that impairs one’s ability to communicate and interact with others.† Various ASD definitions are known to be universal since they recognise it as a spectral condition (Baird et al., 2016). In his study, Umekage (2011, p. 25), indicates that ASD is a hidden disability coupled with foetal brain damage as well as impairment of neural vitro development. Characterised by interests, activities and repetitive behaviours, ASD is so complex that it varies from one case to another (Akanksha et al., 2011). Despite various studies on the reasons, causes and treatment of ASD, there are relatively unknown rationale for its causes. Chandler and Baird (2015, p. 923) posits that people with ASD need different kinds of support since their ways of development and learning differ from every individual. The aim of this paper is to discuss the causes, reasons and treatment of ASD.Causes of ASDAlthough there are undetermined causes of ASD, scientists as well as medical practitioners believe that an amalgamation of genetic and environmental factors are the two major causes of ASD (Fitzgerald and Geschwind, 2013). To start with, the cause of ASD via genetic factors is not a simple process, but a complex of progression that involve multiple genes. Causes of ASD – Gentics Autism Spectrum Disorder As indicated by Schechtman (2014, p.86) study, the rate of ASD development in identical twins as well as monozygotic is higher than rates in dizygotic and same-sex fraternal twins. This indicates that fraternal twins only share some genes, while identical twins have equal genes and therefore genes contributes much to autism. More so, Brothers as well as sisters of children with autism have high level of autism (Fitzgerald and Geschwind, 2013). From another perspective, Smith and John (2011, p. 803) in their research attributed that siblings share certain problems such as language as well as learning difficulties if one of the sibling has autism. However, it is not clear if autism is inherited as well as more general predisposition difficulties.To modify or extend this essay or to get pricing on a custom essay Contact Us TodayCauses of ASD – Environmental Factors Secondly, ASD can be caused by environmental factors. Environmental toxins such as mercury and thimerosoal vaccines cause autism stems (Mercer et al., 2016). More so, congenital rubella infection is one of the environmental factors that cause ASD. However, Goin-Kochel and Myers (2015, p. 172) disputes that there is any clarity environmental factors causing ASD and therefore more studies needs to be done. Rich and Isager (2012, p. 410) adds â€Å"some of the evidence proposed for environmental factors is based on case reports, which are often difficult to interpret.†Reasons for ASDASD as mentioned earlier, ASD can be caused by a combination of environmental and genetic factors, however, we have reasons ASD occurs. First, Autism exists when a single gene known as fragile X syndrome (FXS) exists in the blood (Hessl and Schneider, 2013). FXS is defined as a syndrome that is coupled with autism as well as intellectual disability (Visootsak and Picker, 2015). As per Wehner and Hager man (2011, p. 415), â€Å"Whereas ASD is a behavioural diagnosis, FXS is a medical, or more accurately, a genetic diagnosis and therefore when associated with FXS, ASD is caused by the genetic change or mutation in the Fragile X gene.† This alters normal blood circulation, hence ASD. Secondly, individuals are affected by ASD when tuberous sclerosis, chromosome 15q and other genetic conditions subsist (Hessl and Schneider, 2013).ASD Treatment – MedicationsCore symptoms associated with ASD have no medication and cure, but we have medications that help to manage high energy levels of ASD, seizures, inability to focus as well as depression symptoms (Burrell and Borrego, 2012). The first treatment method utilised during ASD is the early intervention service. This method improves individual’s development, especially children with ASD (Buitelaar and Wong, 2014). These services, such as vitamin therapy, auditory training, facilitated communication and physical therapy improve children talk, interaction and walk. Early intervention services attribute the theory of mind as an explanatory ASD theory that reflects on the symptom criteria (A) of the DSM-5. As per Gallese and Goldman (2012, p. 496), the theory of mind was created by Uta Frith, Alan Leslie and Simon Baron-Cohen in 1985 to explain communication persistence as well as social interaction for people with ASD.ASD Treatment – Behaviours and CommunicationThe second method used for ASD treatment is the behaviours and communication approaches. This method involves direct, organised and structural ways for people with ASD to participate in a given paediatric events and medication. As per Burrell and Borrego (2012, p. 424), applied behaviour analysis (ABA) is utilised as a treatment of ASD via behaviour and communication approach to encourage positive and discourage negative behaviours hence improving various skills needed during ASD treatment. This is in relation to the theory of executive dysfunction which states, â€Å"Executive functions (EF) are a set of cognitive skills that are put into practice through autonomous activities.† Most of these EF skills are utilised by ASD patients to boost their flexibility, organisation, objectives and goals, anticipation as well as to be able to control their impulses (Buitelaar and Wong, 2014). Thirdly, ASD can be treated through dietary approaches. Change in diet, such as using certain foods, mineral supplements and vitamin helps to treat certain ASD effects. However, Talalay and Zimmerman (2014) posit that although dietary approach is considered as one of the ASD treatment, there is no scientific support and recommendation. Finally, ASD can be treated using complementary and alternative treatments. Treatments associated with complementary and alternative approaches include chelation, biological such as secretin, special diets and body-based systems (Burrell and Borrego, 2012).ConclusionIn conclusion, the aim of this paper was to discuss the causes, reasons and treatment of the Autism Spectrum Disorder (ASD). Being a hidden disability coupled with foetal brain damage as well as impairment of neural vitro development, ASD has varied and complex behaviours hence there is unknown treatment for core symptoms. Generally, ASD is caused by a combination of genetic and environmental factors such as genes inheritance and environmental toxins respectively. Some of the treatments for ASD as discussed included the used of the early intervention services, the behaviours and communication approaches, dietary approaches and complementary and alternative treatments. Characterised by interests, activities and repetitive behaviours, ASD is so complex that it varies from one case to another and therefore its treatments depends on an individual case.To modify or extend this essay or to get pricing on a custom essay Contact Us TodayBibliographyAkanksha, M., Sahil, K., Premjeet, S. and Bhawna, K. (2011) â€Å"Autism spectrum disorders(ASD).† International Journal of research in ayurveda & pharmacy, 2(5), pp.1541- 1546. Baird, G., Simonoff, E. and Charman, T. (2016) â€Å"Prevalence of disorders of the autism spectrum in a population cohort of children in South Thames: the Special Needs and Autism Project (SNAP).† The lancet, 368(9531), pp.210-215. Burrell, L. and Borrego, J. (2012) â€Å"Parents’ Involvement in ASD Treatment: What Is Their Role?.† Cognitive and Behavioral Practice, 19(3), pp.423-432. Buitelaar, K. and Wong, C. (2014) â€Å"Psychopharmacological prescriptions for people with autism spectrum disorder (ASD): a multinational study.† Psychopharmacology, 231(6), pp.999-1009. Chandler, S. and Baird, G. (2015) â€Å"Psychiatric disorders in children with autism spectrum disorders: prevalence, comorbidity, and associated factors in a population-derived sample.† Journal of the American Academy of Child & Adolescent Psychiatry, 47(8), pp.921-929. Fitzgerald, R. and Geschwind, D. (2013) â€Å"Autism recurrence in half siblings: strong support for genetic mechanisms of transmission in ASD.† Molecular psychiatry, 18(2), p.137-140. Goin-Kochel, P. and Myers, B. (2015) â€Å"Congenital versus regressive onset of autism spectrum disorders: Parents’ beliefs about causes.† Focus on Autism and Other Developmental Disabilities, 20(3), pp.169-179. Gallese, V. and Goldman, A. (2012) â€Å"Mirror neurons and the simulation theory of mind-reading.† Trends in cognitive sciences, 2(12), pp.493-501. Hessl, D. and Schneider, A. (2013) â€Å"Fragile X Syndrome (FXS). In Encyclopedia of Autism Spectrum Disorders 79(2), pp. 1320-1324. Magalhaes, T. and Almeida, J. (2010) â€Å"Functional impact of global rare copy number variation in autism spectrum disorder.† Nature, 466(7304), pp.368-401. Mercer, L., Creighton, S. and Lewis, S. (2016) â€Å"Parental perspectives on the causes of an autism spectrum disorder in their children.† Journal of Genetic Counseling, 15(1), pp.41-50. Rich, B. and Isager, T. (2012) â€Å"Mortality and causes of death in autism spectrum disorders: an update.† Autism, 12(4), pp.403-414. Sparks, B. and Dager, S. (2012) â€Å"Brain structural abnormalities in young children with autism spectrum disorder.† Neurology, 59(2), pp.184-192. Schechtman, M. (2014) â€Å"Scientifically unsupported therapies in the treatment of young children with autism disorders.† Psychiatric Annals, 37(9), pp. 79-92. Smith, S. and John, W. (2011) â€Å"Col4a1 mutation causes endoplasmic reticulum stress and genetically modifiable ocular dysgenesis.† Human molecular genetics, 16(7), pp.798- 807. Talalay, P. and Zimmerman, A. (2014) â€Å"Sulforaphane treatment of autism spectrum disorder (ASD).† Proceedings of the National Academy of Sciences, 111(43), pp.50-55. Umekage, T. (2011) â€Å"Association of the oxytocin receptor (OXTR) gene polymorphisms with autism spectrum disorder (ASD) in the Japanese population.† Journal of human genetics, 55(3), pp. 23-32. Visootsak, J. and Picker, J. (2015) â€Å"Advances in the treatment of fragile X syndrome.† Pediatrics, 123(1), pp.378-390. Wehner, A. and Hagerman, R. (2011) â€Å"The behavioral phenotype in fragile X: symptoms of autism in very young children with fragile X syndrome, idiopathic autism, and otherdevelopmental disorders.† Journal of developmental & behavioral pediatrics, 22(6), pp.409-417.To modify or extend this essay or to get pricing on a custom essay Contact Us TodayOther Links: Summary Reviewer Admin – Jane Review Date 2017-07-18 Reviewed Item Autism Spectrum Disorder – Causes, Reasons and Treatments Author Rating 5

Law (convention and Individual Ministerial Responsibility) Free Essay Example, 1500 words

The traditional concept of IMR is that the minister is ultimately responsible for all the actions of civil servants under him even though he may not have the knowledge of such actions. A case in point was the resignation of Sir Thomas Dugdale over the Crichel Down case in 1954. The minister of Agriculture resigned despite of the fact that the mistakes within his department were committed without his knowledge with some of the mistakes even deliberately and mischievously committed by the civil servants. The successful invasion of the Falkland Islands by Argentina also prompted the resignation of Lord Carrington, then Foreign Secretary, along with two of his junior ministers. The contention was that they failed to their duties by ensuring a sound Foreign Policy2. However, the convention is now being interpreted such that lack of knowledge no longer makes a minister fully responsible for the actions of his ministry’s civil servants although he is still required to explain to the Parliament. Sir David Maxwell summed it up in the following statement3: â€Å"The Minister is bound to defend action of which he did not know or of which he disapproves. We will write a custom essay sample on Law (convention and Individual Ministerial Responsibility) or any topic specifically for you Only $17.96 $11.86/pageorder now But he remains constitutionally responsible to the Parliament for the fact that something has gone wrong and he alone can tell Parliament what has occurred and rendered an account of his stewardship†. The minister is given four options to give effect to the IMR which are the following4: 1. Inform and Explain The minister is expected to inform the Parliament of any developments and major events within his ministry. He is also expected to explain actions and policies to the same institution. The methods available for the ministers to be able to do this are ministerial statements, green and white papers and consultation papers. 2. Apologise The minister is expected to apologise to the Parliament for any error within his ministry even though this may not directly involve him. 3. Take Action Failure or unsatisfactory affairs within the minister’s sphere of responsibility are expected to be remedied by the minister. This applies whether or not resignation is involved. 4. Resign If the minister has been proven to be negligent of their duties or if he cannot offer any satisfactory explanations for any mishaps within his department then the ultimate recourse for him is to resign his position. As noted earlier, the ministers may not be held responsible for any actions within his ministry that he has no knowledge of but he is still accountable to Parliament.

Different Ways of Learning the Theory of Knowledge Free Essay Example, 1000 words

The reason is one of the important ways of learning in the Theory of Knowledge (TOK). The reasoning is the technique used by most philosophers to arrive at the truth. Reason helps to analyze the situation deeply and take decisions. Reason is not automatic; it comes through experience. Once a king groomed a monkey to be his most trustworthy and natural companion (Ashliman, 2002). The monkey was asked to keep strict vigilance while the king slept one day. The monkey soon found a bee hovering over his master and unable to bear that someone should disturb his master, the monkey drew out his sword and struck down the bee in a single stroke. The same blow split the king s head and any amount of explanation did not matter. The money was shunned by everyone but through this experience, people realized that it is better to have a clever enemy than a foolish friend. This also shows that the power of reasoning increases in times of trouble. Had the kind s head not been smashed, people would ne ver think of anything wrong in having a monkey (or a foolish entity) as a friend. We will write a custom essay sample on Different Ways of Learning the Theory of Knowledge or any topic specifically for you Only $17.96 $11.86/page

Organizational Behavior Individual Assignment Social Media

Organizational Behavior Individual Assignment Social Media in the Workplace Jasmine Powell MGMT 362: Organizational Behavior Instructor: Dr. Audrey J. Brown Week 8: October 18, 2016 Social media in today’s society has becoming the new wave of normal as today’s generation has taken over. The evolution of being connected to the world at all times has just now become the new norm. Some people look at it as a distraction, while others may see it as a major opportunity to turn socializing into a profit. Either way these raise the general question or daily arguments that people share with their debate on the topic. What are considered to be social media sites? Do you think social media should be restricted while at work? What are the pros and cons? What type of social Media are appropriate to use at work? So on and so forth. As today’s work environment has evolved from chatter around the water cooler to a series of â€Å"Likes† and â€Å"Shares† and â€Å"Tweets,† entrepreneurs recognize the influence of social media in the workplace and are looking for ways to maximize the benefits of social media in their own business plans . Social media can be benefiting to the workplace as well by promoting an educating people about different. Pro and Cons The pros and cons Social Media use in the workplace has become a fact of life for employers. Although there are many business purposes for the use of social media, the use by employees both inside and outsideShow MoreRelatedThe Importance Of Interpersonal Skills On The Workplace1695 Words   |  7 Pagesand less stress. Another reason that interpersonal skills are important is because the added organizational behavior element can help promote and improve awareness the social responsibility of a company. 2. What is the definition of organizational behavior (OB)? 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Definition of Marketing Research Free Essays

The first thing that an organization must concentrate upon when going into operations is to analyze the current situation of the environment that it is a part of. The organization must know of the current happenings in the environment and the kind of competitors that it is directly affected by and indirectly affected by as well. All these factors must be analyzed clearly and thoroughly so that the organization can decide its strategies and run them effectively. We will write a custom essay sample on Definition of Marketing Research or any similar topic only for you Order Now In order to do so, the organization must use marketing research as its tool because it is known to be extremely useful and it never provides false results. Through research, the organization can know what the competitors are planning to do and what their line of action is. Marketing research can be defined as â€Å"Market research is broader in scope and examines all aspects of a business environment. It asks questions about competitors, market structure, government regulations, economic trends, technological advances, and numerous other factors that make up the business environment.† (Wikipedia, 2006) Techniques used for Marketing Research Any organization can use marketing research as one of its strongest tools for being competent in a market. It is known to be the research and development area that has allowed the organization to grow and become stronger in the competitive environment. The organization must concentrate on this aspect to grow in any environment. There are several techniques that can be used for marketing research and will be explained below. The broader categorization of marketing research is out into four topics as: 1.  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Qualitative Research 2.  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Quantitative Research 3.  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Observational Research 4.  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Experimental Research (Wikipedia, 2006) The techniques within these topics are surveys, focus groups, observations, personal interviews and field trials. Surveys can be defined as have a list of questions pertaining to the topic of the research and then having the target market, selected for the research, to fill out and answer these questions. The survey allows the organization to have an easy statistical overview of the data representing the market so that the organization can understand what features of the product must be concentrated upon to optimize. There are various different kinds of surveys such as telephone surveys, mail surveys and even in person surveys which means that an individual is asked these questions so that the organization can understand the individual’s requirements and satisfaction from the product or service that the organization is willing to offer. Focus groups are conducted with a group of participants chosen from the target market of the research to understand what emotions and important points can be derived from the discussion of these participants with one another. The organization can also use personal interviews where the same problems could be discussed face to face rather than having a group of people. In this way, only the idea and the perception of that individual can be understood. The observational techniques depend upon the non verbal communication of the target market. There could be people from the organization who could be sitting at certain areas where the competitor’s products are sold and then could observe as to how the people look into the products and what their requirements are or specifications of the product. There could be the possibility that a customer may need a certain color that was demanded by many other customers and many other features. The organization must also look into the field trials which is really the experimental portion of the research. The organization would first collect all the data from the internet and other sources and then analyze the data in order to understand how the product is to be changed in order that the customers needs from the research results can be reached. Once the product is created, it must first be tested in an environment to see whether the product has any flaws in them or not. The organization can then make required changes in the product and then eventually launch their product in the market. This is the entire process of research that is usually followed by many organizations. However, there is a greater participation of internet in this process because of the availability of data at all times. Internet and Its Usefulness in Marketing Research Internet is known to be a very strong tool for research because internet holds all the information that can be available for an individual. The internet can provide laws and regulations imposed by governments on different sectors of a country or the research results of various other companies and individuals who also tried to understand the market. All this information can be sued by an individual or company as secondary data as well as a support for their primary research. A company known as Engro Chemicals Pakistan Limited has grown to be a multinational and is continuing to grow globally. The main aim of this company was to allow the farmers to have higher yield with better products to embed in the soil. Looking at the environmental aspect of agriculture and using the laws and regulations of the government imposed upon agriculture, Engro came up with new technologies along with products to help the farmers grow. The company went through a number of websites and internet sources to understand the requirements of farmers all over the world and got hold of secondary data to understand the gaps within the agricultural sector globally. The company sort out the products that it can produce and then customized them for its market. This provided the company with a competitive edge over all other locally based companies that are still struggling to gain the market. Bibliography 1.  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   All Business. (2006). Market Research Techniques. Retrieved on November 19, 2006 2.  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Asia Market Research. (2002). Research Techniques. Retrieved on November 19, 2006 from: http://www.asiamarketresearch.com/news/cat_research_techniques.htm 3.  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Engro Chemicals Pakistan Limited. Retrieved on November 19, 2006 from: www.engro.com 4.  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Infospan, Inc. Qualitative and Quantitative Techniques. Retrieved on November 19, 2006 5.  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Wikipedia. (2006). Marketing Research. Retrieved on November 19, 2006 from: http://en.wikipedia.org/wiki/Marketing_research       How to cite Definition of Marketing Research, Essays

The Impact of African American Inventors free essay sample

Whether we know it or not, black inventors have impacted our lives drastically. From the time we wake up, until we go back to sleep at night, we use at least one thing that has been made by an African- American inventor. Whether it is something as big as a traffic light or as little as a hair brush, black inventors have made major contributions to our everyday lives. Many people know about the big inventions, but both small and big inventions have impacted America. (Lund 2008) During slavery, most black slaves were denied proper education and many laws were passed in the South prohibiting slave literacy. Even free blacks in the century before and after the Civil War were limited in their access to quality education and career training. This limited education and training meant that, in some way, blacks were shut out of professional occupations and limited to working in industries thought acceptable for them, such as house services and farming. However, a small number of talented blacks were able to attain an education and, through their work, made major contributions to American life. (Imbornoni n. d. ) Unlike black slaves, free blacks prior to the Civil War were allowed to receive patents for their inventions. But, once again, because blacks lacked educational and career opportunities, few had the necessary skills or experience to develop their creative ideas or patent them. Despite these restrictions, there were a number of successful black inventors whose inventions proved useful and important. Thomas Jennings, the first African American to receive a patent, used the money he earned from his invention to fund abolitionist foundations. There were a few slaves, who were good builders, that created devices and techniques that benefited their owners’ enterprises. A decision was made by the federal government in 1858. They said that neither the slave nor the slave owner could claim ownership rights to an invention. After the Civil War the U. S. patent laws were revised so that anyone, no matter what race, could receive a patent. As a result, the number of patents received African Americans rose drastically. By World War I, African Americans had left a permanent mark on the scientific, technological, and industrial development of the United States. (Imbornoni n. d. ) There are many inventions by African Americans that have contributed to the way that our nation is in the present day. There are a lot of major inventions and inventors that we have learned about since we were little kids. For example, we have been taught that George Washington Carver invented peanut agricultural science and we know that Madame C. J. Walker invented cosmetics and hair products for black woman. But there are also a lot of inventors that we don’t know about. For example, Lonnie Johnson invented the Super Soaker and that George Crum invented the potato chip. No matter the size, big and small, inventions made by black people have had major effects on the world. Some of the inventions of these African American scientists and engineers have had such a tremendous impact on American development that they have transformed whole industries. Even though all inventions by blacks have had some kind of impact on this world, there is one person whose invention sticks out among the rest. George Washington Carver probably had the biggest impact on the world. Think about when you eat a peanut butter sandwich or sum peanut butter crackers. You would not be able to do this without him. Every time you see something made out of a peanut you think of him. He came up with more than 300 different ways to use peanuts. Carver devoted his whole life to researching something as little as a peanut to make a humongous contribution to the world. Another great inventor was Granville T. Woods, also known as the Black Edison. He invented many inventions throughout his lifetime. His inventions included the chicken egg incubator, automatic air brakes, and various improvements on railways, such as the steam boiler furnace. Even though he invented all of these things, Granville T. Woods dedicated his life to creating a range of inventions relating to the railroad industry. He invented more than a dozen devices to improve electric railway cars and many more for controlling the flow of electricity. His most famous invention was an invention used to let the engineer know how close the train was to other trains which helped cut down many accidents on the train tracks. (Bellis n. d. ) Garret Morgan was also a great inventor whose invention had a major impact on the world. He had two major inventions in his life: the gas mask and the traffic light. Even though he has invented many things, Garret is known mostly for the traffic light. Take a second and think about what driving would be like without lights to direct traffic at an intersection. There would be a whole lot of accidents every day. Because of this, the impact of his invention is felt by everyone in the world on a daily basis. You cannot drive anywhere, almost, without seeing a traffic light at least one time and, on top of that, they have saved so many lives. Another great inventor who had a very big impact, that most girls would be familiar with, is Madame C. J. Walker. Madame Walker revolutionized the hair care and cosmetics industry for African American women. If it wasn’t for her some of the girls in the world today would look like they got in a fight with a hair dryer. Thank goodness for her major contributions. Another great African American inventor was named Otis Boykin. Otis was known as an electronic phenomenon. He was responsible and well known for the artificial heart stimulator, or pacemaker. Many families are impacted by his invention everyday in the United States because many people have to get pacemakers to live. Even though he is most known for that invention, he is also known for a couple more inventions. Otis invented more than two dozen electronic devices during his lifetime. Even though those are probably the biggest inventions there are many more that we see every day. You could probably see about more than a dozen African American made inventions in one day. For example, if you were a business man/woman. When you wake up in the morning and your hair is all messed up you reach for a brush. This brush was an invention by Lydia Newman, a black woman. Then, when you go to eat or drink, you probably sit at the kitchen table. You wouldn’t be able to do this without the contributions made by H. A. Jackson. After that, most likely, you are on your way to work. While you are on the road you will probably have to go through some traffic lights. These traffic lights were invented by Garrett Morgan in 1923 who also invented the gas mask 1914. If he had not strived to make these lights, automobiles might still be crashing into one another at intersections. Once you finally make it to the office you might have an office on the top floor. Alexander Miles made it possible for you to ride the elevator instead of walking up a lot of stairs. Once the whole day has passed and you are back at home, I’m sure you will need a light and of course that lamp will need a light bulb. The lamp that you might use was invented by Michael C. Harvey and the light bulb by Lewis Latimer. Without the efforts of them, we might still be in the dark. All these inventions can be seen in one day and they are all made by African-Americans. These inventions are incredible and leave a mark on history (Lund 2008). Now that we know so much about black inventors we will know when we see an invention that has come from an African American inventor. We have to learn to appreciate the things that African American inventors have done because if it wasn’t for them the world would be a whole lot different. https://www.thoughtco.com/granville-t-woods-1992675 https://docs.google.com/presentation/d/17cUezVJ0DjwfAeM_HUdLn_wsPTnvmxo4y0QJMWaHBmM/edit https://www.infoplease.com/spot/timeline-key-moments-black-history https://apstudent.collegeboard.org/apcourse/ap-world-history/exam-practice http://boards.straightdope.com/sdmb/archive/index.php/t-416164.html